Climate Change Data

Environmental Metrics

ESG Focus Areas

• Principles
• People
• Product
• Planet

Environmental Achievements

• 12.35% GHG emissions reduction in 2020 compared to 2019, despite over 30% revenue growth
• Repligen Sweden achieved carbon neutrality in manufacturing and uses 100% renewable energy
• Reduced water consumption by 24% at Repligen Sweden between 2018 and 2020
• Implemented corrugated recycling programs at Marlborough and Waltham sites

Social Achievements

• Introduced new leadership development programs and DE&I initiatives
• Donated $100,000 to organizations focused on social equity and racial justice
• 87% employee participation in engagement survey with 81% favorable scores
• Established a DE&I Council

Governance Achievements

• Refreshed Codes of Conduct to reflect commitment to ethical business practices and compliance
• Updated Corporate Governance Guidelines, Code of Business Conduct and Ethics, Business Partner Code of Conduct, and Insider Trading Policy
• Appointed two new Board members, increasing Board diversity

Climate Goals & Targets

Environmental Challenges

• Supply chain disruptions due to COVID-19
• Increased absolute GHG emissions due to business growth
• Data limitations in early ESG reporting
• Managing waste from single-use products

Mitigation Strategies

• Established a COVID-19 Task Force to manage pandemic-related challenges
• Set an aggressive emissions reduction target of 10% for Scope 1 and 2 emissions
• Invested in ESG reporting software for improved data collection and reporting
• Exploring recycling programs for single-use products and improved packaging designs

Supply Chain Management

Supplier Audits: Annual, semi-annual, or for cause audits of 51% of suppliers

Responsible Procurement

• Business Partner Code of Conduct

Climate-Related Risks & Opportunities

Transition Risks

• Regulatory mandates requiring investment in emissions reduction

Reporting Standards

Frameworks Used: GRI Standards: Core option, SASB Medical Equipment and Supplies Standards, UNGC

Certifications: ISO 14001, ISO 45001, ISO 9001:2015, ISO 13485:2016

UN Sustainable Development Goals

• Goal 3: Good Health and Well-being
• Goal 7: Affordable and Clean Energy
• Goal 8: Decent Work and Economic Growth
• Goal 9: Industry, Innovation and Infrastructure
• Goal 10: Reduced Inequalities
• Goal 12: Responsible Consumption and Production
• Goal 13: Climate Action

Repligen's initiatives contribute to these goals through various programs and actions detailed in the report.

Sustainable Products & Innovation

• Right-sized packaging for key products
• KrosFlo® TFDF® system

Awards & Recognition

• Award of Excellence for Exceptional Efforts as a Critical Supplier

Environmental Metrics

ESG Focus Areas

• Environmental Impacts (Energy/Emissions, Water, Waste)
• Social Impacts (Talent Engagement and Development, Value Chain Engagement, Community Engagement)
• Governance Impacts (Structure and Practices, Policies and Charters, Risk Management)

Environmental Achievements

• Reduced greenhouse gas (GHG) emissions intensity by 40% from 2020 to 2022 on a revenue-normalized basis
• Transitioned to 100% renewable electricity at 9 of 18 manufacturing sites by year-end 2022, representing 75% of our total global energy consumption and 62% of total emissions
• Added Scope 3 emissions tracking and benchmarking (in addition to Scope 1 and Scope 2), for 9 of 15 categories as defined by the GHG Protocol
• Established detailed waste tracking and reduction mechanisms with monthly review by leadership steering committee

Social Achievements

• Completed engagement survey in first half 2023 with >90% participation and 76% favorability rating
• Formalized diversity, equity, and inclusion (DEI) programs; set and achieved reach goals for gender diversity, expanded awareness events
• Launched global intranet 'The R Circle', introduced sustainability newsletter 'Blue Marble', and formed three new Employee Resource Groups (ERGs)
• Increased volunteerism with a record 16 sites participating in annual Community Outreach Week; contributed over $300,000 to support underrepresented groups and local communities

Governance Achievements

• Fortified cybersecurity systems and protocols to follow CIS 20 Controls and implemented a Zero Trust framework
• Introduced the Repligen Performance System (RPS) for continuous operational process improvement
• Expanded Enterprise Resource Planning system (SAP) from 9 to 13 sites, covering 76% of manufacturing footprint
• Initiated cross-functional risk management program to identify, prioritize, and mitigate operational, reputational, and strategic risks
• Updated charters and policies to maintain strong governance practices

Climate Goals & Targets

Environmental Challenges

• Post-use product recycling

Mitigation Strategies

• Gained actionable knowledge and discovered opportunities for success in other areas
• Pilot single-use recycling program with select customers (in progress)

Supply Chain Management

Supplier Audits: Pilot study with 12% of suppliers in 2022-2023 using EcoVadis

Responsible Procurement

• EcoVadis engagement

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI Universal Standard 2021, SASB Standards, TCFD, UNGC

UN Sustainable Development Goals

• Not disclosed

Awards & Recognition

• UNGC 2022 SDG Pioneer, USA Network award
• Sustainalytics Low-risk Rating
• Sustainalytics Top Rated awards (Industry and Regional)

Environmental Metrics

ESG Focus Areas

• Products & Packaging
• Operations
• Talent
• Supply Chain
• Communities
• Partnerships & Pathways

Environmental Achievements

• Powered 13 of 18 manufacturing sites with 100% renewable electricity (up from 9 of 18), representing 88% of our total global consumption (up from 82%) and 72% of total emissions (up from 62%).
• Achieved an 86% reduction in product weight, a 98% reduction in product footprint, and an estimated average 86% reduction in shipping-related emissions for the CTech™ BEAMS™ System.
• Launched new, 100% recyclable packaging made from plant fiber for Spectrum® Hollow Fiber Filters, resulting in significant reductions in the average weight of packaging material per unit (81%), shipping volume (90%), and shipping-related carbon emissions (83%).
• Launched flat-pack controller cart packaging for the XCell™ Lab System, resulting in a 57% smaller shipping crate by volume and using 78% less plastic cushioning material.

Social Achievements

• Rolled out progressive talent development and pipeline programs to address feedback from our 2023 employee engagement survey, which had 90% participation and a 76% favorability rating.
• Increased the percentage of women in management from 27% to 29% and the percent of our global employee base represented by women employees from 34% to 35%.
• Focused on DEI education and recruiting efforts contributing to a near 50/50 balance of U.S. employees self-reporting as either white or people of color in 2023.
• Awarded €600,000 training grant by Ireland’s Investment Development Authority to implement a comprehensive strategic talent development plan over the next three years.

Governance Achievements

• Improved our risk management and sustainability management capabilities for the future; selected a more robust software platform, being implemented in 2024.
• Committed to net-zero emissions by 2050 with the Science Based Targets initiative (SBTi).
• Maintained an MSCI AA “Leader” rating within the Health Care Equipment and Supplies constituent group and Low Risk by Morningstar Sustainalytics with recognition as an ESG Industry “Top Rated” company.
• Received four silver and one bronze site-level EcoVadis scores based on customer evaluations of Repligen sustainability practices as a supplier.

Climate Goals & Targets

Environmental Challenges

• Supply chain disruptions due to climate events
• Need for better communications around risk identification, mitigation and adaptation strategies.
• Challenges in tracking and quantifying the full impact on our emissions inventory for Scope 3 emissions, specifically categories 11 (Use of Sold Products) and 12 (End-of-Life Treatment of Sold Products).

Mitigation Strategies

• Developed alternative sourcing strategies
• Modified Repligen approach to sustainability reporting, focusing on progress made in key impact areas instead of categorizing E, S and G separately.
• Investing in a new risk management software platform.
• Continued to strengthen our emissions inventory data for nine Scope 3 categories to better inform our overarching emissions reduction strategy.

Supply Chain Management

Supplier Audits: All suppliers complete a questionnaire; critical suppliers are audited every 3-5 years.

Responsible Procurement

• Business Partner Code of Conduct

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events

Transition Risks

• Regulatory changes, market shifts

Opportunities

• Development of energy-efficient products

Reporting Standards

Frameworks Used: GRI, SASB, TCFD, UNGC

Certifications: ISO 13485:2016, ISO 14001:2015

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Goal 3
• Goal 5
• Goal 8
• Goal 9
• Goal 12
• Goal 13
• Goal 16

Not disclosed

Sustainable Products & Innovation

• CTech™ BEAMS™ System
• OPUS® Pre-packed Chromatography Columns
• Spectrum® Hollow Fiber Filters
• XCell™ Lab System

Awards & Recognition

• Not disclosed