Climate Change Data

Environmental Metrics

ESG Focus Areas

• Corporate Governance
• Gender Diversity
• Risk Management

Social Achievements

• No specific social initiatives mentioned, but the company states it does not discriminate based on gender in setting salary levels, training and development, or advancement opportunities.

Governance Achievements

• The company followed most of the ASX Corporate Governance Council recommendations, with explanations provided for deviations.

Climate Goals & Targets

Environmental Challenges

• The company did not have a documented procedure for evaluating the performance of the board, its committees, and directors; lack of a nomination committee, audit committee, and risk committee; lack of a formal director induction program; and lack of an internal audit function.

Mitigation Strategies

• Informal performance evaluations were conducted; board members assumed the responsibilities of the missing committees; the company stated that the size of the company did not warrant the establishment of separate committees; and the company considered its systematic monitoring of control activities sufficient to manage risks.

Supply Chain Management

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: ASX Corporate Governance Council Principles and Recommendations

Environmental Metrics

ESG Focus Areas

• Environmental
• Social
• Governance

Social Achievements

• Maintained a stable workforce despite intense competition for talent, with female employees representing 60% of the workforce.

Governance Achievements

• Established an ESG framework to manage risks and opportunities and meet stakeholder expectations.

Climate Goals & Targets

Environmental Challenges

• Delays in data outcomes from two COVID-19 studies due to decreased severe disease cases and difficulty recruiting participants.
• Challenges presented by the COVID-19 pandemic, including lockdowns, social distancing, and limitations on face-to-face meetings and travel.

Mitigation Strategies

• Worked to ease the burden on employees during the pandemic.
• Established an ESG framework to address material ESG issues.

Supply Chain Management

Climate-Related Risks & Opportunities

Environmental Metrics

ESG Focus Areas

• Environmental
• Social
• Governance

Environmental Achievements

• Promote a flexible working environment that may reduce emissions from commuting

Social Achievements

• Nurturing a culture where diverse talent thrives
• Promoting a flexible working environment to enable a better work-life balance, improving employee wellbeing

Governance Achievements

• Assessed ESG matters that are material to our business
• Operating within the established framework that will drive our efforts to realise the opportunities we see, manage the risks to our business and ensure we are meeting the expectations of stakeholders

Climate Goals & Targets

Environmental Challenges

• Clinical trial risks (delays, costs, potential product liability claims)
• Commercialisation risk (uncertainty of third-party interest and acceptable terms)
• Competition risk (rapid innovation, obsolete products)
• Arrangements with third-party collaborators (reliance on partners)
• Intellectual property risks (patent uncertainty, infringement)
• Regulatory risk, reimbursement approvals and government policy (changes in laws and regulations)
• R&D reimbursement risk (eligibility changes)
• Reliance on key personnel (loss of services)
• Human resources (competition for qualified personnel)
• Future capital requirements (substantial funding needed)
• Loss or theft of data (privacy breaches)

Mitigation Strategies

• Releases material updates on the status of the ACTION3 clinical trial to ASX
• Focus on drug discovery and development to a stage of value determination leading to commercial realisation (trade sale or license)
• Continuous monitoring of the competitive landscape to identify, assess and minimise any IP risks, and to strengthen the Dimerix IP position
• Hiring sufficiently qualified and skilled management and scientific development staff
• Complying with applicable privacy data protection laws and undertaking measures to prevent and detect privacy breaches

Supply Chain Management

Climate-Related Risks & Opportunities

Environmental Metrics

ESG Focus Areas

• Sustainability
• People
• Diversity

Social Achievements

• Continued investment in people and resources for a world-class culture.
• Focus on improving and evolving work culture.
• Commitment to nurturing a culture where diverse talent thrives.

Governance Achievements

• The board of directors is responsible for determining and reviewing compensation arrangements for key management personnel.

Climate Goals & Targets

Environmental Challenges

• Clinical trial risks (delays, costs, product liability)
• Commercialization risk (finding partners, acceptable terms)
• Competition risk (innovation, market changes)
• Risks associated with third-party collaborators
• Intellectual property risks (patent grants, protection)
• Third-party intellectual property infringement claims
• Non-intellectual property litigation, claims, and disputes
• Trade secret risks
• Regulatory risk, reimbursement approvals, and government policy changes
• R&D reimbursement risk
• Reliance on key personnel
• Human resources challenges (attracting and retaining talent)
• Future capital requirements
• Loss or theft of data

Mitigation Strategies

• Close collaboration with IQVIA (CRO) for ACTION3 trial.
• Progressing commercial manufacturing capabilities.
• Seeking licensing partners, multiple term sheet offers received.
• Engaging patent attorneys for intellectual property strategy.
• Implementing measures to prevent and detect data breaches.
• Hiring sufficiently qualified and skilled management and scientific development staff.

Supply Chain Management

Climate-Related Risks & Opportunities

Awards & Recognition

• Blake Award for Excellence 2024