Climate Change Data

Environmental Metrics

ESG Focus Areas

• Antimicrobial Resistance (AMR)
• Water and environment
• Improving access
• Science and Innovation
• Climate and energy
• Responsible procurement

Environmental Achievements

• Hit the vast majority of environmental targets for 2020
• Semi-synthetic penicillin (SSP) API product range meets PNEC discharge targets set by the AMR Industry Alliance two years ahead of schedule
• Received EcoVadis Gold sustainability rating (top 4% of companies in the “Manufacture of basic pharmaceutical products and pharmaceutical preparations” industry)
• Reduced carbon footprint by up to 65% compared with the traditional chemical process for PureActives®

Social Achievements

• Expanded CSR approach in India and Mexico with positive impact on health and education
• Appropriate Antibiotic Use project in China rolled out across 70 hospitals
• Launched several fitness-driven initiatives for employees (health check-up camps, fitness bikes, fitness dance sessions, yoga day, Happy Garden initiative)
• Launched the TOR scheme for older employees in the Netherlands to improve work-life balance
• Launched Centrient Young Professionals Network

Governance Achievements

• Introduced PSCI principles and PSCI audit programme in own operations and full supply chain
• First AMR supplier assessment survey done
• Developed a Sustainability Assessment Tool (SAT)
• Implemented Sustainability Assessment through the Self-Assessment Questionnaire (SAQ)
• Adopted Guidelines for Disciplinary Sanctions

Climate Goals & Targets

Environmental Challenges

• Some 2020 objectives will go unrealised
• Climate change and AMR posing a growing threat
• Drug shortages due to fragile supply chain and price competition
• Increased public and governmental scrutiny on environmental impact
• Increased stakeholder scrutiny on AMR from antibiotic pollution

Mitigation Strategies

• Developing the next stage of our Sustainability Strategy (Roadmap for 2025 and beyond)
• Working with customers, suppliers and other partners to drive industry awareness and action on critical sustainability issues
• Engaging with stakeholders to raise awareness of supply chain vulnerability
• Expanding supply footprint and ensuring product registrations to reach patients globally
• Implementing the AMR Industry Alliance’s Common Antibiotic Manufacturing Framework
• Achieving PNEC compliance for SSPs
• Developing environmental KPIs for 2021-2025
• Implementing corrective and preventive measures to address key findings after audits

Supply Chain Management

Supplier Audits: 73 audits in 2018 and 2019

Responsible Procurement

• Supplier Code of Conduct
• PSCI principles
• Sustainability Assessment Tool (SAT)
• Self-Assessment Questionnaire (SAQ)

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI

Certifications: ISO 14001 (except China)

UN Sustainable Development Goals

• 3
• 6
• 12
• 13

The report details how initiatives contribute to these goals.

Sustainable Products & Innovation

• PureActives®

Awards & Recognition

• 2018 GSK Environmental Sustainability Suppliers Award

Environmental Metrics

ESG Focus Areas

• Minimising environmental impact
• Improving human health and social impact
• Acting responsibly

Environmental Achievements

• 14% carbon emission reduction (against 2015 baseline)
• 10% solid waste reduction (against 2015 baseline)
• 50% improvement in relative CO2 efficiency
• 45% energy reduction
• 25% water reduction
• 100% PNEC compliant across the entire supply chain of oral antibiotics
• Integrated sustainability assessment into project management and capital expenditure approval processes
• Launched ESG Ambition 2021–2030

Social Achievements

• Donated nearly 60,000 face masks and installed two oxygen plants in hospitals in India during COVID-19
• Reached 100,000 people in 100 hospitals throughout China with an awareness campaign on AMR
• Installed 280 solar-powered streetlights in four villages near Toansa plant
• Introduced new Centrient Code of Conduct and Business Partner Code of Conduct
• Introduced SpeakUp platform for reporting breaches of the Code of Conduct
• Established Human Rights Committee
• Renovated two schools in Toansa, India

Governance Achievements

• Increased female representation on Executive Committee and Board of Directors
• Introduced a refined purpose, vision and strategy for the company

Climate Goals & Targets

Environmental Challenges

• COVID-19 impact on operations and supply chains
• Drug shortages due to fragile supply chain
• Antimicrobial resistance (AMR)
• Reducing scope 3 emissions

Mitigation Strategies

• Established local and global task forces to address COVID-19 challenges
• Implemented multi-supplier strategy to secure supply chain
• Developed comprehensive approach to eliminate AMR from wastewater treatment operations
• Developed an internal AMR survey for assessing AMR risks in the antibiotic supply chain
• Working on aligning climate targets with science-based targets (SBTs)

Supply Chain Management

Supplier Audits: 13 PSCI sustainability audits conducted in 2021, with 5 more planned for 2022. 73 suppliers passed ESG assessments.

Responsible Procurement

• Business Partner Code of Conduct
• Sustainability self-assessment questionnaire (SAQ)
• PSCI principles
• AMR survey

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI Standards: Core option

Certifications: ISO 14001

UN Sustainable Development Goals

• 3
• 6
• 12
• 13

Centrient links its material topics and efforts to SDGs 3 (Good Health and Well-being), 6 (Clean Water and Sanitation), 12 (Responsible Consumption and Production), and 13 (Climate Action).

Sustainable Products & Innovation

• PureActives® range of APIs and FDFs

Awards & Recognition

• EcoVadis Gold Sustainability rating (2020 and 2021)

Environmental Metrics

ESG Focus Areas

• Antimicrobial resistance
• Water and environment
• Improving access
• Science and Innovation
• Climate and energy
• Waste management
• Responsible procurement
• Human capital development
• Human rights
• Patient safety
• Community impact

Environmental Achievements

• 5% carbon emissions reduction compared to 2015 baseline
• 10% energy intensity reduction compared to 2021 baseline
• 25% electricity sourced from renewable sources
• 97% of waste repurposed compared to 2015 baseline
• 10% water consumption reduction compared to 2021 baseline
• 100% compliance with PNEC limits
• Santa Perpetua site (Spain) certified under AMR Industry Alliance scheme

Social Achievements

• Established a Mobile Healthcare Unit in Toansa, India, benefitting more than 1,200 people in 2023
• Reached 2,500 people impacted by the 2023 Toansa flooding by distributing essential medicines and hygiene kits
• Impacted more than 45,000 lives around the world through CSR programme
• 97% of eligible employees completed Code of Conduct certification (2023)
• Completed Human Rights Impact assessment
• Developed and established a Sustainable Sourcing Policy
• Improved gender balance at senior level, with 30% of senior management roles held by women
• Launched a Centrient Community Action strategy and framework
• Facilitated 1.5 billion patient treatments globally (2023)

Governance Achievements

• Maintained Gold rating for EcoVadis Supplier Assessment in 2022 and 2023
• Completed the Human Rights Impact assessment
• Developed and established a Sustainable Sourcing Policy

Climate Goals & Targets

Environmental Challenges

• Supply chain disruptions
• Global shortages of essential medicines
• Growing demand for medicines
• Antimicrobial resistance (AMR)

Mitigation Strategies

• Multi-supplier strategy to avoid dependence on single suppliers
• Backward-integrated production for better supply chain control
• Capacity increase projects at Toansa (India), Yushu (China), and Ramos Arizpe (Mexico)
• Sustainable Antibiotics programme to reduce antibiotic emission and prevent AMR
• 100% compliance with PNEC target values for all wastewater streams
• Collaboration with AMR Industry Alliance and BSI for AMR certification

Supply Chain Management

Supplier Audits: 10 key suppliers assessed in 2023; 6 PSCI sustainability audits conducted in 2022-2023

Responsible Procurement

• Business Partner Code of Conduct (BPCoC)
• Sustainability self-assessment questionnaire (SAQ)
• PSCI principles
• AMR survey

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Development of energy-efficient products

Reporting Standards

Frameworks Used: GRI Core Option, UN Sustainable Development Goals (SDGs)

Certifications: ISO 14001

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• 3
• 6
• 12
• 13

Centrient's initiatives contribute to these goals through improving access to medicines, responsible water and waste management, sustainable energy use, and climate action.

Sustainable Products & Innovation

• PureActives® range of enzymatically produced antibiotics

Awards & Recognition

• Gold Sustainability Rating from EcoVadis (2022 and 2023)

Environmental Metrics

ESG Focus Areas

• Environmental
• Social
• Governance
• Antimicrobial Resistance (AMR)

Environmental Achievements

• 97% of waste repurposed (compared to 2021 baseline)
• 10% water consumption reduction (compared to 2021 baseline)
• 25% electricity sourced from renewable sources (compared to 2015 baseline)
• 46.2% absolute reduction in scope 1 and 2 greenhouse gas emissions by 2031 (target)
• 27.5% absolute reduction in scope 3 greenhouse gas emissions by 2031 (target)

Social Achievements

• Facilitated 1.5 billion patient treatments globally (2023)
• 97% of all eligible employees completed Code of Conduct certification (2023)
• Launched a Centrient Community Action strategy and framework
• Established a Mobile Healthcare Unit in Toansa, India, benefitting more than 1,200 people in 2023
• Impacted more than 45,000 lives around the world through CSR programs and activities
• Reached 2,500 people impacted by the 2023 Toansa flooding by distributing essential medicines and hygiene kits

Governance Achievements

• Maintained 100% compliance with PNEC limits
• Certified Spain site under new AMR IA scheme
• Introduced shadow carbon pricing evaluation for key investments
• Climate targets validated by the Science Based Targets initiative (SBTi)
• Reported data to the Carbon Disclosure Project for the first time in July 2023
• Developed and established a Sustainable Sourcing Policy
• Maintained EcoVadis Gold rating in 2022 and 2023

Climate Goals & Targets

Supply Chain Management

Responsible Procurement

• Sustainable Sourcing Policy

Climate-Related Risks & Opportunities

Sustainable Products & Innovation

• PureActives (enzymatic platform)