Climate Change Data

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability

Environmental Achievements

• Met 2012 water conservation target ahead of schedule
• Met 2012 energy reduction target ahead of schedule
• Met 2012 waste (recycling) target ahead of schedule
• Reduced energy use by 520,000 GJ (2008-2010)
• Reduced CO2 emissions by 46,000 MT (2008-2010)
• Recycled 58.5% of waste in 2010
• Improved U.S. fleet vehicle fuel efficiency by 3 MPG (2007-2010)

Social Achievements

• Maintained a top-tier safety record in the industry
• Implemented a global tobacco-free policy
• Launched an online wellness program
• Organized environmental volunteer activities (beach and park cleanups)

Governance Achievements

• Established a sophisticated data management system for environmental data
• Engaged with internal and external stakeholders to shape environmental sustainability plan
• Environmental Sustainability Council guides the plan and reports to the Corporate Responsibility and Compliance Committee of the Board of Directors

Climate Goals & Targets

Environmental Challenges

• Understanding and measuring the effects of conservation progress within the context of a changing business
• Potential climate change risks (extreme weather, water scarcity, increasing regulation)
• Increased waste generation due to increased operations

Mitigation Strategies

• Tying reporting of conservation progress to specific projects and initiatives
• Implementing plans to mitigate climate change risks (business continuity planning, water conservation efforts, monitoring carbon regulations)
• Shifting efforts to waste reduction, improving processes and changing work culture to use fewer materials

Supply Chain Management

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events
• Water scarcity

Transition Risks

• Increasing regulation

Reporting Standards

Frameworks Used: GRI G3 Guidelines (Application Level C)

Third-party Assurance: Third-party assessment of environmental data systems, processes, and controls; moving toward future third-party assurance

Awards & Recognition

• Numerous awards from local municipalities for waste reduction, resource conservation, and wastewater discharge compliance

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability

Environmental Achievements

• Exceeded energy, water, and waste reduction targets set for 2012.
• Reduced energy usage by approximately 181,000 gigajoules and CO2 emissions by 15,000 metric tons.
• Saved almost 2,000 cubic meters of water per year in Rhode Island through staff initiative.
• Recycled 72 percent of treated wastewater in Puerto Rico.
• Diverted more than 30 metric tons of waste from landfills through composting in Colorado.
• Completed renovation of an office building in Thousand Oaks, California, designed to achieve LEED Gold status.

Social Achievements

• Staff members participated in International Coastal Cleanup, removing more than two metric tons of debris.
• Amgen Foundation supported various environmental organizations focusing on water quality and environmental education.

Governance Achievements

• Not disclosed

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Not disclosed

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: Null

Certifications: Null

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• Amgen named Energy Partner of the Year in Colorado

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability

Environmental Achievements

• Reduced energy use by 919,000 GJ (12% of 2007 baseline)
• Reduced carbon dioxide emissions by 83,000 MT (18% of 2007 baseline)
• Reduced water use by 690,000 m³ (7% of 2007 baseline)
• Improved waste recycling rate from 38% to 59%
• Reduced waste by 1,094 MT (7% of 2007 baseline)
• Improved US sales fleet fuel efficiency by 5 MPG (23% of 2007 baseline)
• LEED Gold certification for building renovation in Thousand Oaks, CA
• New manufacturing building in Puerto Rico reduced energy use by 25% and fuel requirements by 40% compared to traditional methods, eliminating 8,730 metric tons of carbon dioxide in 2012
• Switching to advanced chromatography methods leading to energy and water conservation, waste reduction, and reduced solvent use
• Approved use of paperboard from certified-sustainable forests in secondary packaging
• Expanded printing of recycling logos on secondary packaging

Social Achievements

• Comprehensive and effective staff wellness programs
• One of the best safety records in the industry
• Amgen staff volunteered in communities worldwide, removing nearly four metric tons of trash during the 2012 International Coastal Cleanup
• Amgen was awarded the Boulder County, Colorado, Parks and Open Space Partnership Award for conservation activities
• Amgen Foundation supported water conservation through the National Fish and Wildlife Foundation’s Five Star Restoration Program and other environmental initiatives

Governance Achievements

• Not disclosed

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Not disclosed

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events

Transition Risks

• Increasing regulation

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: GRI G3.1

Certifications: Null

Third-party Assurance: Bureau Veritas

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• Boulder County, Colorado, Parks and Open Space Partnership Award

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability

Environmental Achievements

• Reduced facility carbon emissions by 8,000 MT from 2012 baseline
• Reduced waste to landfill or incineration by 320 MT from 2012 baseline
• Reduced water use by 19,000 m3 from 2012 baseline
• Achieved 40% increase in energy efficiency at corporate headquarters resulting in savings of more than 28,000 gigajoules of energy and 2,197 metric tons of carbon
• Drug product manufacturing building in Puerto Rico earned LEED certification
• New Singapore facility will have a one-third smaller footprint compared with traditional facilities
• More than $24 million in cost savings from environmental initiatives

Social Achievements

• Staff volunteer work in community environmental projects (International Coastal Cleanup, Reef Check)
• Amgen Foundation supported community-based wetland, riparian and coastal habitat restoration projects
• Amgen Foundation made grants to EarthCorps Stewardship Volunteers and the Washington Trails Association Youth Trail Stewardship programs

Governance Achievements

• Not disclosed

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Not disclosed

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events

Transition Risks

• Increasing regulation

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: GRI G3.1

Certifications: LEED (Puerto Rico facility)

Third-party Assurance: Bureau Veritas

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• Listed on the 2013 Dow Jones Sustainability North America Index

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability
• Employee Safety and Wellness
• Governance

Environmental Achievements

• Reduced carbon emissions by 94,000 metric tons from 2008 through 2014
• Realized more than $21 million in cost savings through energy conservation projects (2008-2014)
• Increased recycling rate from 35% to 50% from 2007 through 2014
• Next-Generation Biomanufacturing facility in Singapore expected to conserve water and energy by approximately 80 percent, reduce carbon emissions by approximately 75 percent, and significantly reduce the amount of solid waste produced compared with conventional biomanufacturing.
• Drug-product development building in Thousand Oaks, California earned LEED Platinum certification.

Social Achievements

• Received numerous sustainability acknowledgements in 2014, including being named to the Dow Jones Sustainability World Index for the first time and maintaining its position on the North America Index.
• Amgen staff avoided approximately 536 metric tons of greenhouse gas emissions in 2014 through sustainable commuting.
• Amgen celebrated Earth Day at most of its US-based locations in 2014, promoting greener practices.

Governance Achievements

• Amgen reports in alignment with the Global Reporting Initiative (GRI) G3.1 guidelines.
• 2014 environmental data underwent limited assurance by Bureau Veritas.

Climate Goals & Targets

Environmental Challenges

• Integrating environmental sustainability practices across all operations
• Managing energy and water consumption in buildings
• Reducing waste to landfill and incineration

Mitigation Strategies

• Implementing energy conservation and carbon reduction projects
• Piloting an integrated data management system to improve building performance
• Analyzing data from waste audits to shape initiatives for recycling and waste reduction
• Using data from water maps to identify opportunities for conservation
• Integrating low-water landscaping and smart-irrigation controls

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Not disclosed

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events

Transition Risks

• Increasing regulation

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: GRI G3.1

Certifications: LEED Platinum

Third-party Assurance: Bureau Veritas

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Next-Generation Biomanufacturing technologies

Awards & Recognition

• Dow Jones Sustainability World Index
• Dow Jones Sustainability North America Index
• LEED Platinum certification
• Corporate Energy Management Award from the Association of Energy Engineers

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability

Environmental Achievements

• Reduced carbon emissions by 97,500 metric tons (23%) from 2008 to 2015.
• Conserved 106,000 cubic meters of water in 2015.
• Diverted 90 metric tons of waste from landfill for recycling.

Social Achievements

• Amgen staff participated in environmental volunteering events (International Coastal Cleanup, Clean Up Australia Day).
• Amgen Foundation supported environmental education initiatives (NatureBridge school programs).

Governance Achievements

• Not disclosed

Climate Goals & Targets

Environmental Challenges

• Drought conditions in California and Puerto Rico.
• Recycling challenges due to local waste management services.

Mitigation Strategies

• Accelerated water conservation efforts in California and Puerto Rico.
• Partnered with a vendor to expand recycling services for previously un-recyclable waste items.

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Not disclosed

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events

Transition Risks

• Increasing regulation

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: GRI

Certifications: Null

Third-party Assurance: Bureau Veritas

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Next-Generation Biomanufacturing technologies

Awards & Recognition

• Dow Jones Sustainability World Index
• Newsweek Green Rankings

Environmental Metrics

ESG Focus Areas

• Business Ethics
• Environment
• Workplace
• Access to Medicine
• Community Commitment

Environmental Achievements

• Met 2020 carbon and water environmental targets ahead of schedule
• Reduced carbon emissions by 126,000 metric tons (30%) from 2007 through 2018 by implementing energy conservation and carbon reduction projects
• Exceeded 2020 carbon targets for fleet vehicles and facility operations

Social Achievements

• 100% of staff completed Code of Conduct training
• 52% of global workforce is female
• Amgen Foundation Science Education programs reached more than 7 million students
• Medicines donated through Direct Relief reached more than 7,000 patients in 18 low- and middle-income countries
• Amgen Safety Net Foundation provided nearly $5.5 billion of support to patients in the U.S. since 2008

Governance Achievements

• Established a new, executive-level governance council to oversee corporate responsibility
• 100% on Human Rights Campaign’s Corporate Equality Index

Climate Goals & Targets

Environmental Challenges

• Falling short of the safety goal of 0.27 incidents or less per 100 staff (with a rate of 0.41)

Mitigation Strategies

• Continued focus on new and improved ways to promote staff safety
• Revitalized safety campaign focusing on behaviors and commuting safety

Supply Chain Management

Supplier Audits: Annual assessment and monitoring of key suppliers

Responsible Procurement

• Supplier Sustainability Program addressing business ethics, labor and human rights, and environmental impacts

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: UN Global Compact, SDGs, GRI, CDP, SASB

Third-party Assurance: Bureau Veritas North America (limited assurance)

UN Sustainable Development Goals

• SDG 3: Good Health and Well-being
• SDG 4: Quality Education
• SDG 12: Responsible Consumption and Production
• SDG 9: Industry, Innovation and Infrastructure
• SDG 17: Partnerships for the Goals

Amgen's activities align with these SDGs through access to medicine, science education, environmental sustainability, innovation, and partnerships.

Sustainable Products & Innovation

• Next-generation biomanufacturing technology

Awards & Recognition

• Association of Energy Engineers 2017 Energy Project of the Year award
• AHA’s Gold Level Workplace Health Achievement award
• Corporate Social Responsibility Program of the Year award (Ireland Pharma Industry)

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability
• Diversity, Inclusion, and Belonging
• Ethical Research
• Business Ethics
• Access to Medicine
• Responsible Sourcing
• Community Investment
• Governance

Environmental Achievements

• Met and exceeded most 2020 environmental targets well ahead of schedule
• Reduced carbon emissions by 33% since 2007
• Reduced water use by 30% since 2007
• Reduced waste disposed of by 28% since 2007

Social Achievements

• Provided $1.5 billion worth of medicines at no cost to low-income patients in the US through the Amgen Safety Net Foundation
• Launched RISE initiative to increase diversity in clinical trials
• Expanded existing programs to support employee health and wellness, including mental health
• Amgen Foundation committed $7.5 million to support organizations advancing social justice and fighting systemic racism

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic
• Social injustice issues
• Healthcare disparities
• Lack of diversity in clinical trials
• Affordability of medicines

Mitigation Strategies

• Swift action to protect employee health and well-being
• Expanded benefits including mental health benefits
• Launched RISE and Lazarex programs to increase diversity in clinical trials
• Amgen Foundation increased investments to organizations working toward racial equality
• Flexible pricing approaches to improve patient access
• Patient support programs and donations
• Health systems strengthening

Supply Chain Management

Supplier Audits: ~65% of total supplier spend

Responsible Procurement

• Supplier Code of Conduct

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: SASB Biotechnology & Pharmaceuticals Sustainability Accounting Standard, TCFD reporting standard, UN Global Compact, Sustainable Development Goals

Third-party Assurance: Limited assurance by Apex Companies, LLC

UN Sustainable Development Goals

• Goal 3: Good health and well-being
• Goal 4: Quality education
• Goal 8: Decent work and economic growth
• Goal 13: Climate action
• Goal 17: Partnerships for the goals

Sustainable Products & Innovation

• Next-generation biomanufacturing

Awards & Recognition

• Barron’s 100 Most Sustainable Companies
• Dow Jones Sustainability Indices
• Forbes America’s Best Employers for Diversity
• Military Times Best Place for Vets
• Great Place to Work Institute
• Corporate Equality Index
• InHerSight Best Biotechnology Companies for Women
• American Heart Association’s Workplace Health Achievement Index

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability
• Diversity, Inclusion & Belonging
• Access to Medicines
• Health Equity
• Responsible Sourcing
• Corporate Governance
• Business Ethics
• Ethical Research
• Patient Safety and Product Quality
• Cybersecurity and Data Privacy

Environmental Achievements

• Reduced carbon emissions by 36% from 2020
• Reduced water usage by 117,000 cubic meters from 2020
• Reduced waste disposed primarily due to an increase in waste-to-energy conversion
• Renewable energy sources provided 79% of Amgen’s total electricity consumption in 2021, up from 41% in 2020
• Three Amgen sites did not send any waste to landfills in 2021

Social Achievements

• Continued efforts to improve workforce diversity
• Provided additional mental health resources to support employees
• Continued work toward increasing ethnic and racial diversity of participants in clinical trials through RISE initiative
• Pledged to double business with diverse suppliers and triple business with Black-owned suppliers by 2023
• Provided approximately $2.2 billion of Amgen medicines at no cost to uninsured or underinsured patients in the US
• Provided 900,000 daily doses of medicines at no cost in over 20 low- and middle-income countries

Governance Achievements

• Included ESG performance in Company goals under annual incentive compensation plan
• Developed a wide range of external disclosures to communicate on ESG performance
• Maintained a diverse and independent Board of Directors

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic impacting employee health and safety, supply chain, and clinical trials
• Underrepresentation of racial and ethnic minority patients in clinical trials
• Access challenges to medicines for uninsured or underinsured patients
• Climate change risks to operations and lung health

Mitigation Strategies

• Implemented additional safety measures at manufacturing and research sites, provided remote work support and mental health resources
• Developed enterprise-wide framework to enhance diversity and representation in clinical trials, partnered with community organizations
• Implemented patient support programs and worked with partners to expand access to medicines
• Announced aspiration to achieve net-zero carbon emissions by 2027, invested in renewable energy and sustainable manufacturing

Supply Chain Management

Supplier Audits: ~70% of total supplier spend in 2021

Responsible Procurement

• Supplier Code of Conduct
• Supplier Sustainability Program
• Supplier Diversity Program

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather, flooding

Transition Risks

• Regulatory changes, market shifts

Opportunities

• Development of energy-efficient products

Reporting Standards

Frameworks Used: Biopharma Investor ESG Communications Guidance, SASB, TCFD, UN Global Compact, UN Sustainable Development Goals

Third-party Assurance: Reasonable assurance audit for 2021 environmental data

UN Sustainable Development Goals

• Goal 3: Good Health and Well-being
• Goal 4: Quality Education
• Goal 9: Industry, Innovation and Infrastructure
• Goal 13: Climate Action

Amgen's mission to serve patients, science education programs, innovative manufacturing processes, and commitment to carbon neutrality

Sustainable Products & Innovation

• FleXBatch manufacturing technology

Awards & Recognition

• Dow Jones Sustainability Indices World and North America Index inclusion
• American Heart Association Workplace Health Achievement Index Gold Recognition
• Barron’s 100 Most Sustainable Companies list
• Newsweek’s America’s Most Responsible Companies list
• Corporate Equality Index perfect score
• Military Friendly Employer Silver Recognition
• Just 100 List
• THQSE Silver Medal ranking
• Forbes America’s Best Employers for Diversity and New Grads

Environmental Metrics

ESG Focus Areas

• Water Security
• Environmental Sustainability
• Climate Change

Environmental Achievements

• Reduced water consumption by an unspecified percentage from 2021 levels; 23% progress towards a 40% reduction target by 2027 from a 2019 baseline.
• Reduced total water withdrawals and discharges compared to 2021.
• Implemented water-saving and water efficiency projects across global manufacturing and R&D sites.
• Introduced reverse osmosis technology in Thousand Oaks, saving 71,000 cubic meters of water annually.
• Singapore facility reduced water use by 54% compared to conventional facilities.
• Amgen Singapore's wastewater treatment plant saves 25,500 cubic meters of water annually.

Social Achievements

• Provided fully functioning, safely managed WASH services to all workers.
• Engaged in community volunteer efforts such as International Coastal Cleanup.

Governance Achievements

• Board-level oversight of water-related issues.
• ESG goals included in annual incentive plan for all staff.

Climate Goals & Targets

Environmental Challenges

• Potential supply restrictions from municipal water supplies affecting manufacturing processes.
• Water stress in some operational regions (26-50% of withdrawals from water-stressed areas).
• Acute physical risks from wildfires (Thousand Oaks), hurricanes (Puerto Rico), and other extreme weather events impacting supply chains.
• Potential for disruption in global supply chain due to extreme weather events.

Mitigation Strategies

• Investment in water-smart technologies/processes.
• Implementation of water conservation and reuse strategies.
• Water-reduction plans and strategic consolidation of facilities.
• Wildfire, red flag warning, and severe weather playbooks and facility construction with fire-resistant materials.
• Redundant power generation sources and fuel contracts at manufacturing sites.
• Highly efficient cogeneration plant at Puerto Rico facility.
• Qualitative and quantitative risk assessments to inform resilience strategies.
• Supplier Code of Conduct requiring suppliers to reduce their environmental footprint.

Supply Chain Management

Supplier Audits: 76-99% of suppliers through EcoVadis

Responsible Procurement

• Supplier Code of Conduct

Climate-Related Risks & Opportunities

Physical Risks

• Wildfires
• Hurricanes
• Droughts

Opportunities

• Improved water efficiency

Environmental Metrics

ESG Focus Areas

• Environmental Sustainability
• Access to Healthcare
• Health Equity
• Human Capital Management
• Diversity, Inclusion & Belonging
• Community Investment
• Corporate Governance
• Business Ethics
• Ethical Research & Development, Product Quality and Patient Safety

Environmental Achievements

• Achieved 54% of our targeted reduction for carbon, 34% of our targeted reduction for water and 54% of our targeted reduction for waste disposed (against 2019 baseline).
• Renewable electricity accounted for 90% of total purchased electricity consumption.
• New Ohio biomanufacturing facility built to LEED Gold standards and includes solar arrays.

Social Achievements

• Provided $2.5 billion of Amgen medicines at no cost to eligible uninsured or underinsured patients in the U.S.
• Launched a five-year program with World Child Cancer to improve the lives of children with Burkitt lymphoma.
• Held first Health Equity Challenge, awarding grants to community-based organizations to improve health in Black communities.
• 79% of employees responding to Global Engagement Survey would recommend Amgen as a great place to work.
• Increased number of Amgen ERG chapters around the world by 13%.

Governance Achievements

• 100% of employees trained on Amgen Code of Conduct.
• Established Amgen AI Governance Council and adopted Trustworthy AI framework.

Climate Goals & Targets

Environmental Challenges

• Climate change physical risks (extreme precipitation, wildfires, rising temperatures)
• Climate change transition risks (new regulations, supply chain adaptability, low-emission technology availability)
• Health equity disparities
• Lack of diversity in clinical trials

Mitigation Strategies

• Integrating environmental sustainability into business strategy and investment decision-making.
• Engaging with suppliers on decarbonization efforts, increasing electrification of processes, increasing renewable energy use.
• Implementing Diversity Action Plans for nearly every Amgen-sponsored clinical trial.
• Partnering with organizations to address health equity gaps (e.g., Robert A. Winn Diversity in Clinical Trials Award Program).

Supply Chain Management

Supplier Audits: Increased number of suppliers monitored through EcoVadis by 18% in 2023.

Responsible Procurement

• Supplier Code of Conduct
• Formalized expectations for engaging with suppliers to support adoption of science-based targets.

Climate-Related Risks & Opportunities

Physical Risks

• Extreme precipitation
• Wildfires
• Rising temperatures
• Rising sea levels

Transition Risks

• New regulations
• Supply chain adaptability
• Low-emission technology availability

Reporting Standards

Frameworks Used: CDP, SASB, SBTi, TCFD, UN Global Compact, UN SDGs

Certifications: LEED Gold

Third-party Assurance: Third-party assurance of selected environmental and safety data

UN Sustainable Development Goals

• Goal 3: Good Health and Well-being
• Goal 4: Quality Education
• Goal 5: Gender Equality
• Goal 8: Decent Work and Economic Growth
• Goal 9: Industry, Innovation and Infrastructure
• Goal 10: Reduced Inequalities
• Goal 13: Climate Action

Amgen contributes to these SDGs through its core business, corporate philanthropy and the activities of its foundations.

Sustainable Products & Innovation

• Packaging that was 57% smaller and plastic-free for two products in Canada.

Awards & Recognition

• America’s Best Employers for New Grads
• America’s Best Large Employers by Forbes
• America’s Climate Leaders by USA Today
• America’s Most JUST Companies by Just Capital
• The 14 Most Important Players in Corporate Philanthropy by Inside Philanthropy