Climate Change Data

Environmental Metrics

ESG Focus Areas

• Patient Safety & Quality Management
• Innovation & Business Model Resilience
• Affordability & Access
• Business Ethics & Ethical Marketing
• Corporate Governance
• Supply Chain & Materials Management
• Human Resources & Diversity, Equity, & Inclusion

Environmental Achievements

• Implemented motion-sensor lights, smart heating/cooling systems, filtered water units, and an in-office composting program in Cambridge office.

Social Achievements

• Launched Sage Citizen initiative, supporting communities through essential services and social connection programs; hosted 12 volunteer activities with over 900 volunteer hours impacting over 2,500 people.
• Launched a review of clinical development and recruiting processes to improve diversity and inclusivity of future trials.
• Developed a DE&I strategy, launched DE&I council and 5 BRGs, and implemented employee mentorship programs.

Governance Achievements

• Established an ESG Project Team; implemented an Enterprise Risk Assessment process; maintained a Code of Business Conduct and Ethics with annual training; established a robust cybersecurity program with annual assessments and monthly employee training; implemented ethical marketing practices with cross-functional review of promotional materials.

Climate Goals & Targets

Environmental Challenges

• Minimizing environmental impact given reliance on third-party CROs and CMOs.
• Improving diversity and inclusion across clinical trials and the workforce.

Mitigation Strategies

• Focus on employee-led green initiatives in the office; review of clinical development and recruiting processes to improve diversity and inclusivity; DE&I strategy and initiatives.

Supply Chain Management

Responsible Procurement

• Rigorous vendor qualification process involving onsite audits, review of procedures and practices, facility tours, and interviews with front-line workers.

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: SASB, GRI