Climate Change Data

Modalis Therapeutics Corporation

Climate Impact & Sustainability Data (2022)

Reporting Period: 2022

Environmental Metrics

ESG Focus Areas

  • Environment
  • Social
  • Governance

Environmental Achievements

  • Implemented wastewater treatment at US R&D facility
  • Promoted energy consumption reduction and optimization through facility design, telework, and new HVAC/LED systems
  • Implemented paperless initiatives and 100% recycling of items like toner cartridges
  • Strict enforcement of proper separation and disposal of laboratory waste

Social Achievements

  • Developed therapeutics targeting rare genetic disorders, aligning with the corporate philosophy of 'every life deserves attention'
  • 51% female employees and 16% international employees at US R&D facility (as of Dec 31, 2022)
  • Flexible work schedules and efforts to improve the working environment
  • Securing and developing talent among scientists to drive innovation
  • Making CRISPR-GNDM® technology available to partners to promote open innovation

Governance Achievements

  • Five out of six Board of Directors are Outside Directors (one foreign, one female)
  • Established auditing committee with three members having voting rights
  • Separation of decision-making related to business matters and auditing functions
  • Established Compliance Committee to ensure adherence to laws, business ethics, and company regulations

Climate Goals & Targets

Long-term Goals:
  • Commoditization of genetic analysis
  • Public acceptance of gene therapy
  • Evolution of gene therapy technologies
Medium-term Goals:
  • Clinical proof of concept for MDL-101 (2024-2025)
  • Market approval and launch of GNDM-based product(s)
Short-term Goals:
  • MDL-101 PreIND filing in 1Q 2023
  • Initiation of clinical trial for MDL-101

Supply Chain Management

Climate-Related Risks & Opportunities