Climate Change Data

Environmental Metrics

ESG Focus Areas

• Patients
• People
• Community
• Planet

Environmental Achievements

• Decreased energy consumption by 25,850 kWh and water use by 1,000 m3 at Villa Guardia facility
• Sourced 100% of electricity from wind at Athlone facility
• Over 90% of water used at our largest contracted cannabis growing site is from rainwater harvesting
• Redesigned Epidiolex packaging to reduce shipping weight, resulting in GHG emissions reduction of 14.24 tonnes of C02e, reduction in total energy use of 122.7 gigajoules, savings of 333.4 tonnes of water, and reduction in solid waste generation of 1.13 tonnes

Social Achievements

• Launched Employee Value Proposition (EVP) focusing on Connection to People, Growth & Development, Flexibility & Balance, and Health & Well-being
• Launched Jazz Remix flexible work model
• Launched Employee Diversity, Equity, Inclusion and Belonging Program
• Conducted more than 35 clinical trials with partners in 2021
• Announced a 3-year research collaboration with Stand Up to Cancer for $4 million
• Partnered with a Children’s Oncology Group (COG) to conduct a Phase 2/3 clinical trial under Real Time Oncology Review Program
• Donated thousands of doses of oncology medication to countries in Africa, Southeast Asia and South America

Governance Achievements

• Established strong governance around ESG program with Board oversight from Nominating and Corporate Governance Committee (NCGC)
• Achieved a 50% diverse Board of Directors in 2021, with four female Directors, one Director identifying as BIPOC, and one Director identifying as LGBTQ2+
• Introduced I-CARE (Integrity, Compliance, Accountability, Respect, and Ethics) Comprehensive Compliance Program
• 100% of Jazz employees completed mandatory Code of Conduct and Anti-Bribery & Corruption training

Climate Goals & Targets

Environmental Challenges

• Supply chain disruptions (driver shortages, port delays, supply/cost issues relating to vehicle parts and materials)

Mitigation Strategies

• Adopted strategies to mitigate supply chain disruptions
• Leveraged internal teams to negotiate with suppliers to ensure warehouse capacity
• Maintained good relationships with principal direct suppliers through continuous engagement

Supply Chain Management

Responsible Procurement

• Endeavor to source materials, equipment and other supplies with environmental sustainability; manage environmental and social risks from contract growing, commodity sourcing and the use of GMOs; Supplier Code of Conduct adopted

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI, SASB

Environmental Metrics

ESG Focus Areas

• Patients
• People
• Community
• Planet
• Governance

Environmental Achievements

• Athlone manufacturing site purchases 100% renewable electricity
• Over 50% of electricity purchased at Villa Guardia manufacturing site is from renewable sources
• Implemented energy efficiency and conservation measures at Athlone, Kent Science Park, and Villa Guardia manufacturing sites (LED light conversions, energy-efficient chiller replacements, electric vehicle charging stations)

Social Achievements

• Launched a company-wide Global Volunteer Day
• Provided mentorship to students interested in pursuing healthcare careers
• Offered pro bono legal and other services to promote healthy and well-functioning societies
• Consistently achieved employee engagement survey participation rates above 75%
• Updated Global Employee Referral Policy

Governance Achievements

• Undertook an in-depth materiality assessment
• Updated terms of reference for the Nominating and Corporate Governance Committee in 2021 to reflect expanded remit for ESG oversight
• Introduced the Science and Medicine Committee to the Board of Directors in April 2022
• 100% of full-time employees completed compliance training in 2022

Climate Goals & Targets

Environmental Challenges

• Reducing greenhouse gas emissions
• Further reducing environmental footprint
• Improving data collection frameworks and reporting across CSSI strategy, including environmental performance
• Managing risks associated with water stress at a growing site

Mitigation Strategies

• Developing a comprehensive approach to tracking and reducing GHG emissions (measuring Scope 1 and 2 emissions)
• Developing a strategy to reduce emissions in 2023
• Implementing efficient water management practices
• Evaluating internal reporting processes to determine the feasibility of future disclosures related to SASB metrics

Supply Chain Management

Responsible Procurement

• Standards of Conduct for Supply Chain (outlining expectations for human rights, fair treatment of workers, elimination of human trafficking and slavery)

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI, SASB

Certifications: ISO 14001:2015 (Villa Guardia site)

UN Sustainable Development Goals

• Goal 3: Good Health and Well-being
• Goal 5: Gender Equality
• Goal 8: Decent Work and Economic Growth
• Goal 10: Reduced Inequalities
• Goal 12: Responsible Consumption and Production
• Goal 13: Climate Action
• Goal 16: Peace, Justice and Strong Institutions

Jazz aims to align its CSSI strategy with these SDGs through its initiatives related to patient care, employee wellbeing, community engagement, and environmental stewardship.

Awards & Recognition

• MMIT Patient Access Award for work in narcolepsy

Environmental Metrics

ESG Focus Areas

• Patients
• People
• Community
• Planet

Environmental Achievements

• Athlone, Villa Guardia, and Kent Science Park sites purchased 100% renewable electricity in 2023.
• Athlone site reduced energy use by approximately 20% from 2022 to 2023 despite increased production.

Social Achievements

• Launched an initiative to ensure clinical trial participants reflect the diversity of patient populations.
• Employee engagement surveys consistently achieved participation rates above 75%, with positive results in 2023 (85% connected to purpose, 81% recommending Jazz as a workplace).
• Provided patient advocacy and charitable support of more than $7.5 million to over 78 organizations globally.

Governance Achievements

• Established a governance structure to drive the execution of the CSSI strategy, with accountability assigned to members of the Executive Committee.
• Board is 92% independent.

Climate Goals & Targets

Environmental Challenges

• Increasing sustainability reporting regulations (e.g., EU CSRD and ESRS).

Mitigation Strategies

• Preparing for expanded ESG disclosures in line with ESRS (first publication in 2026).
• Undertaking a double materiality assessment in 2024 to inform ESRS disclosures.

Supply Chain Management

Responsible Procurement

• Standards of Conduct for Supply Chain (outlines expectations for suppliers regarding human rights, fair labor practices, and elimination of human trafficking and modern slavery).

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: GRI, SASB

Certifications: ISO 14001:2015 (Villa Guardia site)