Climate Change Data

Environmental Metrics

ESG Focus Areas

• Product responsibility
• Green chemistry
• Climate change mitigation
• Supply chain engagement
• People
• Business ethics and compliance

Environmental Achievements

• Reduced solvent (particularly DMF) consumption by 23.5% in 2023 compared to 2022 (2.6 metric tons relative to kg manufactured products vs 3.4 metric tons/kg).
• Improved energy efficiency to 16.1 MWh/kg manufactured product (2022: 22.1 MWh/kg).

Social Achievements

• Increased employee base by 5.5% average FTEs in 2023.
• Reduced lost time injuries (LTI) to eleven (2022: 11), resulting in 0.14 lost working days per employee (2022: 0.8).
• Employee engagement survey participation rate of 89% (2022: 74%) with an overall engagement score of 3.6 (2022: 3.7).

Governance Achievements

• No significant instances of non-compliance with laws and regulations in 2023.
• Two reports received through whistleblower hotlines, both withdrawn and unsubstantiated.

Climate Goals & Targets

Environmental Challenges

• Growing manufacturing volumes impacting on-time-in-full delivery performance (OTIF) to 85% (2022: 92%) and customer satisfaction (NPS 62.5 in early 2024 vs 70 in early 2023).
• Customer adjustments to drug development priorities in a tougher funding climate.
• Rising energy prices and increasing customer expectations related to climate matters.
• Potential harm to employees’ health, communities, and the environment from the use of hazardous chemicals.
• Insufficient supply chain engagement, including neglecting human rights, potentially affecting stakeholders and harming communities.
• Increased production volumes potentially impacting employee health and well-being.
• Lack of compliance with EHS requirements potentially resulting in fines, reputational damage, or impact on licenses to operate.
• Non-adherence to applicable laws, rules, regulations, ethical standards, internal policies and procedures, or loss of sensitive data, potentially leading to business interruptions, legal prosecution, and reputational damage.

Mitigation Strategies

• Targeted organizational changes and process improvements.
• Capacity expansion efforts with capital expenditures of EUR 54.9 million.
• Commitment to Green chemistry and continuous energy efficiency improvements.
• Development and launch of a greenhouse gas emission reduction program in 2024.
• Implementation of an integrated EHS management system and ISO 14001 certification at manufacturing sites.
• Promoting circular waste management and solvent recycling.
• Supplier Code of Conduct and Global Supply Chain Policy on Child Labor.
• Risk-based supplier assessment and engagement.
• GMP certified manufacturing sites with established HR and EHS functions.
• Training programs in compliance with GMP requirements and safety regulations.
• Annual performance evaluation and employee development processes.
• Code of Business Conduct and Ethics, internal policies and procedures, and whistleblower programs.

Supply Chain Management

Supplier Audits: Nine selected high-risk tier 1 raw material suppliers participated in assessments in 2023.

Responsible Procurement

• Supplier Code of Conduct (updated in 2023)
• Global Supply Chain Policy on Child Labor (2023)

Climate-Related Risks & Opportunities

Transition Risks

• New legislative and regulatory requirements
• Rising energy prices

Opportunities

• Cost savings from emission reductions and increased energy efficiency

Reporting Standards

Frameworks Used: GRI Standards

Certifications: GMP (all six manufacturing sites), ISO 14001 (four of six manufacturing sites), ISO 45001 (two of six manufacturing sites)

UN Sustainable Development Goals

• SDG 3
• SDG 5
• SDG 8
• SDG 9
• SDG 12
• SDG 13
• SDG 16

Contribution to relevant SDG targets outlined in the report.