Climate Change Data

Environmental Metrics

ESG Focus Areas

• Environmental
• Safety
• Diversity, Culture and Community

Environmental Achievements

• Reduced indirect CO2e emissions for North Billerica facility by greater than 99% by exclusively purchasing renewable wind energy.
• Annual waste reductions achieved in lead, radiological waste, wooden pallets, with an increase in mixed recycling and paper shred recycling at North Billerica and Somerset facilities.

Social Achievements

• Began work on a patient registry to understand the real-world benefits of PYLARIFY, with a focus on enrolling a diverse set of patients, particularly African American men.
• Partnered with national prostate cancer advocacy groups and academic centers on several initiatives to address health disparities.
• Developed a robust onboarding program, reinforced company culture and launched development programs for emerging talent.
• Opened a new corporate office designed to foster a collaborative environment for both remote and onsite teams.
• Employee Resource Groups continue to be a strategic enabler of diversity, equity, inclusion and belonging (DEI&B) strategy.

Governance Achievements

• Amended and restated Bylaws in 2022 to implement majority voting in uncontested elections of directors.
• Amended and restated Bylaws in 2021 to implement proxy access rights for stockholders.
• Amended and restated Charter to eliminate certain supermajority voting requirements and to permit holders of at least a majority of common stock to call special meetings of the stockholders.

Climate Goals & Targets

Environmental Challenges

• Reduced site occupancy and changes in manufacturing activities due to the COVID-19 pandemic.

Mitigation Strategies

• Transitioned Pandemic Response Team to a Return to Office Team to plan the safe return of non-critical workforce back to offices.
• Maintained certain COVID-19 policies to ensure a safe work environment and maintain compliance with applicable regulatory agencies.

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Supplier Code of Conduct requiring suppliers to operate in an environmentally responsible manner and provide a safe and healthy work environment.

Climate-Related Risks & Opportunities

Awards & Recognition

• Ranked as one of the top women-led businesses in Massachusetts

Environmental Metrics

ESG Focus Areas

• Diversity
• Ethics and Compliance
• Environmental Sustainability
• Employee Wellbeing
• Supply Chain Responsibility

Environmental Achievements

• Developed a stormwater management operations and maintenance plan to minimize stormwater pollution.
• Track and monitor energy use, water use, greenhouse gas emissions, and waste generation.

Social Achievements

• Over half of Vice Presidents and above are women.
• Approximately 50% of employees are women.
• Sponsor three Employee Resource Groups.
• Mandatory employee training includes anti-bribery/anti-corruption rules.
• Seek to do business with minority-owned, female-owned, and other diverse businesses.

Governance Achievements

• Formal Ethics and Compliance Committee.
• Supplier Code of Conduct.

Climate Goals & Targets

Environmental Challenges

• Competition in the radiopharmaceutical industry.
• Fragile and unstable global supply of Mo-99.
• Dependence on third-party manufacturers and suppliers.
• Potential generic competition for DEFINITY.
• Expiration of TPT Status for PYLARIFY.
• Regulatory uncertainties and changes in healthcare reimbursement policies.
• Cybersecurity threats.

Mitigation Strategies

• Establishing additional PET manufacturing facilities (PMFs).
• Diversifying Mo-99 supply chain.
• Building an in-house manufacturing facility for DEFINITY.
• Actively pursuing patents for PYLARIFY and DEFINITY.
• Advocating for adequate reimbursement for PYLARIFY.
• Investing in cybersecurity services, technologies, and capabilities.
• Comprehensive cybersecurity awareness training for employees.

Supply Chain Management

Supplier Audits: At least annually

Responsible Procurement

• Supplier Code of Conduct

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: Null

Certifications: Null

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• PYLARIFY AI presentation awarded Top Rated Oral Presentation at the European Association of Nuclear Medicine meeting