Climate Change Data

Environmental Metrics

ESG Focus Areas

• Access to Innovative and Safe Cancer Medicines
• Community Engagement and Advocacy
• Our People and Culture
• Environmental Management

Environmental Achievements

• New state-of-the-art facility operates with a 100% carbon-neutral energy footprint and uses 100% electric power
• Reduced CO2 emissions by over 840 U.S. tons (March 2019-February 2020) through commuter support programs
• Reduced CO2 emissions by over 624 U.S. tons in 2020 due to remote work during the COVID-19 pandemic
• Reduced CO2 emissions by over 924 U.S. tons (July 2021-June 2022) after resuming commuter support programs

Social Achievements

• Launched Employee Giving and Volunteer programs
• 100% employee participation in DEI survey
• 250 managers engaged in sensitivity training focused on DEI
• Employee turnover consistently below average for the U.S. life sciences industry

Governance Achievements

• Established a comprehensive Business Continuity Management Program (BCMP) in 2021
• Implemented robust cybersecurity and information security program
• Maintains a review and approval process for all promotional material

Climate Goals & Targets

Environmental Challenges

• Underrepresentation of racial and ethnic communities in clinical research
• Balancing patient access to Exelixis products with the investments needed for future innovation
• Maintaining business continuity throughout the value chain

Mitigation Strategies

• Launched ‘Inclusiveness Initiative’ to increase diversity in clinical trials
• Providing discounts and rebates to insurers and financial assistance to patients
• Engaging with a third-party partner to track supplier risk, maintaining risk assessment registries, and identifying secondary and tertiary suppliers for raw materials

Supply Chain Management

Responsible Procurement

• Rigorous auditing of third-party materials and service suppliers, both before and after entering into a contract

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: UN Sustainable Development Goals, SASB

UN Sustainable Development Goals

• Goal 3: Good Health and Well-being
• Goal 5: Gender Equality
• Goal 8: Decent Work and Economic Growth
• Goal 9: Industry, Innovation and Infrastructure
• Goal 12: Responsible Consumption and Production

Exelixis' initiatives contribute to these goals through various programs and activities detailed in the report.

Environmental Metrics

ESG Focus Areas

• Access to Innovative and Safe Cancer Medicines
• Community Engagement and Advocacy
• Our People and Culture
• Environmental Management

Environmental Achievements

• 1951 Harbor Bay Parkway building received LEED BD+C Gold Certification
• Implemented a system that tracks the company’s energy and natural gas usage
• Improved van pool program, nearly doubling the number of vehicles from 2022

Social Achievements

• Expanded Inclusiveness Initiative to increase diverse patient representation in clinical trials
• Launched a new website for Exelixis Access Services (EASE)
• Exelixis employees supported more than 1,200 nonprofit organizations through Employee Giving and Volunteer Programs
• Enhanced employee development and benefit programs and progress on DEI initiatives

Governance Achievements

• Maintained a robust cybersecurity and information security program
• No monetary losses in 2022 from legal proceedings associated with false marketing claims
• Over 99% of employees completed all required trainings in 2022

Climate Goals & Targets

Environmental Challenges

• Underrepresentation of diverse communities in clinical trials
• Financial obstacles for patients accessing cancer care
• Balancing patient access with investments in R&D

Mitigation Strategies

• Inclusiveness Initiative with targeted recruitment strategies
• Exelixis Access Services (EASE) programs for financial assistance
• Disciplined approach to R&D, prioritizing high-standard assets

Supply Chain Management

Responsible Procurement

• Rigorous vendor selection and monitoring, assessing factors such as environmental, health, and safety matters, human rights, and regulatory compliance

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: UN SDGs, SASB Standards

Certifications: LEED BD+C Gold

UN Sustainable Development Goals

• Good Health and Well-being
• Industry, Innovation and Infrastructure
• Decent Work and Economic Growth
• Gender Equality
• Responsible Consumption and Production

Initiatives align with these SDGs through various programs and commitments

Awards & Recognition

• LEED BD+C Gold Certification

Environmental Metrics

ESG Focus Areas

• Access to Innovative and Safe Cancer Medicines
• Community Engagement and Advocacy
• Our People and Culture
• Environmental Management

Environmental Achievements

• Developed and implemented an energy dashboard to track electricity and natural gas usage at the Alameda campus.
• Improved understanding of electricity and natural gas usage and enhanced sustainability practices at Alameda headquarters.

Social Achievements

• Amplified corporate initiatives focused on improving the lives of cancer patients, including the "Clinical Trial Inclusiveness Initiative" to enhance accessibility and diversity of clinical trials.
• Gave back to more than 1,700 nonprofit organizations through Employee Giving and Volunteer Programs (EGVP), with employees volunteering over 5,600 hours since 2022.
• Enhanced talent management programs with new educational offerings and fostered a culture of belonging with the addition of a new Employee Resource Group.

Governance Achievements

• Maintained a robust compliance program with over 99% of employees completing required trainings in 2023.
• Established the Exelixis Leadership Foundations, a two-year leadership program for managers.

Climate Goals & Targets

Environmental Challenges

• Corporate restructuring plan in January 2024 resulted in a 14% decrease in the workforce in the first six months of 2024.

Mitigation Strategies

• Corporate restructuring plan aimed to rebalance cost structure, reduce real estate commitments and expenses, and terminate certain licensing partnerships.

Supply Chain Management

Responsible Procurement

• Assessment of potential CMOs for regulatory or quality issues, product recalls, workforce training, human rights abuses, regulatory violations, and embargoes or sanctions.

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: UN SDGs, SASB (now part of IFRS Foundation)

Certifications: LEED BD+C Gold Certification (1951 Harbor Bay Parkway building)

UN Sustainable Development Goals

• Good Health and Well-being
• Industry, Innovation and Infrastructure
• Decent Work and Economic Growth
• Gender Equality
• Responsible Consumption and Production

Initiatives align with these SDGs through various programs and activities described in the report.