Cell Source, Inc.
Climate Impact & Sustainability Data (2020, 2022)
Reporting Period: 2020
Environmental Metrics
Climate Goals & Targets
Environmental Challenges
- Limited operating history and history of operating losses.
- Substantial doubt about ability to continue as a going concern.
- Need to secure additional financing.
- Default on payment obligations under promissory notes.
- Lack of active liquid trading market for common stock.
- Highly concentrated voting power among insiders.
- Potential product and clinical trials liability.
- Liabilities related to working with hazardous materials.
- Foreign exchange fluctuations.
- COVID-19 pandemic impact on preclinical studies and clinical trials.
Mitigation Strategies
- Active negotiations to raise additional capital through debt and equity financings.
- Negotiations with noteholders to extend maturity dates or convert debt to equity.
- Plans to obtain liability insurance coverage.
- Monitoring COVID-19 impact and adapting preclinical studies and clinical trials as needed.
Supply Chain Management
Climate-Related Risks & Opportunities
Reporting Period: 2022
Environmental Metrics
Climate Goals & Targets
Medium-term Goals:
- Introduce approved VETO CAR-T product to high-profile US HSCT centers by 2028-2029.
- Show sustained tolerance post-transplant without need for daily anti-rejection therapy for Veto Cell Organ Transplantation by 2025-2026.
Short-term Goals:
- Commence multi-center registration study for VETO CAR-T (with and without HSCT) by 2026-2027.
Environmental Challenges
- Limited operating history and history of operating losses.
- Substantial doubt about ability to continue as a going concern.
- Default on payment obligations under promissory notes.
- Lack of active liquid trading market for common stock.
- Highly concentrated voting power among insiders.
- Potential product and clinical trials liability.
- Risks related to working with hazardous materials.
- Potential for regulatory approvals to be withdrawn or delayed.
- Potential for products to not gain market acceptance.
- Dependence on licensed patents from Yeda Research and Development Limited.
- Dependence on collaborative partners and service providers.
- Inability to keep up with rapid technological developments.
- Reliance on key personnel.
- Exposure to foreign exchange fluctuations.
- Potential for securities class action litigation.
Mitigation Strategies
- Active negotiations to raise additional capital.
- Efforts to obtain liability insurance coverage.
- Compliance with applicable environmental laws and regulations.
- Development of clinical trial protocols with experienced medical practitioners.
- Implementation of safety procedures for handling hazardous materials.
- Hedging arrangements to minimize foreign exchange fluctuations.
- Maintenance of confidentiality agreements with employees and third parties.
Supply Chain Management
Climate-Related Risks & Opportunities
Sustainable Products & Innovation
- Veto Cell technology