Climate Change Data

Environmental Metrics

ESG Focus Areas

• Patient Support
• Employee Wellness
• Diversity, Equity, and Inclusion
• Environmental Impact
• Community Service

Environmental Achievements

• Increased recycling efforts
• Provided reusable cups to employees
• Installed electric car chargers
• Limited waste in food service distribution

Social Achievements

• Operated a robust patient support program
• Engaged with patient advocacy groups
• Invited patients to share their experiences
• Implemented initiatives to enhance board and workforce diversity
• Advanced the development of diverse talent at all levels
• Ensured diverse succession plans for both employee workforce and board
• Put in place several financial wellness programs (Employee Stock Purchase Plan and 401(k) match program)
• Promoted physical and mental wellbeing (virtual and onsite fitness classes, access to mental health services)

Governance Achievements

• Women hold 30% of board seats and comprise 50% of the executive committee

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic impacting engagement with healthcare professionals and patients
• Supply chain disruptions
• Competition from other pharmaceutical and biotechnology companies

Mitigation Strategies

• Pivoted to a remote and hybrid model for field-based teams
• Implemented remote working policy for employees
• Continued to progress a robust pipeline of earlier-stage research
• Continued efforts to ensure successful commercialization of ARIKAYCE
• Expanded commercial activities in Europe and pre-commercial activities in Japan

Supply Chain Management

Climate-Related Risks & Opportunities

Environmental Metrics

ESG Focus Areas

• Environmental
• Social
• Governance

Environmental Achievements

• Supported several green measures at headquarters (motion-sensor lighting, LED lighting, electric vehicle charging stations, energy-efficient HVAC units, low-flow flushers, responsible hazardous waste management, biodegradable cafeteria products, grease disposal program, electronics recycling program, cooler return service).

Social Achievements

• Named the No. 1 company to work for in the biopharma industry by Science magazine's 2021 Top Employers Survey.
• Became Great Place to Work-certified in the U.S.
• Employee turnover rate below industry benchmark (12.9%).
• 97% of employees said they are proud to be a member of their respective teams.
• 100% of employees said they are determined to give their best effort each day.
• Investing in employees’ physical and mental health (onsite fitness center, online mental wellness platform, dogs at work policy, wellness rooms).

Governance Achievements

• Formalized ESG approach by creating an ESG working group.
• Sharpened commitment to ESG measures.
• Global Healthcare Compliance Program implemented to prevent, detect, and correct violations.

Climate Goals & Targets

Environmental Challenges

• Rapid growth of the company during the pandemic.
• Supply chain disruptions due to the COVID-19 pandemic.
• Ongoing challenges of the global COVID-19 pandemic impacting commercial performance.

Mitigation Strategies

• Embraced a flexible approach to work that persisted beyond the pandemic.
• Fostered an environment where employees could bring their best selves to work.
• Implemented COVID-19 safety measures (remote work, vaccination requirements).
• Continued to advance post-marketing confirmatory, frontline clinical trial program for ARIKAYCE.

Supply Chain Management

Climate-Related Risks & Opportunities

Awards & Recognition

• No. 1 biopharmaceutical company to work for by Science magazine
• Great Place to Work-certified

Environmental Metrics

ESG Focus Areas

• Access to Medicine
• Clinical Trial Safety
• Product Social Responsibility
• Product & Service Safety
• Human Capital Development
• Business Ethics
• Waste Management
• Environmental Management & Policy
• Climate Change & GHG Emissions
• Energy Management & Usage
• Employee Engagement & Satisfaction
• Supply Chain Management
• Ethical Marketing
• Diversity, Equity & Inclusion
• Data Privacy & Cybersecurity
• Board Composition & Leadership
• Board Oversight of ESG
• Whistleblower Program

Environmental Achievements

• Recycled 46.8 tons of waste at headquarters and 7.8 tons at the primary research and development site in 2022.
• Recycled more than 300 lbs of electronics and repurposed 235 items in 2022.

Social Achievements

• More than 500 Insmed employees participated in the inaugural Global Day of Good, donating over 2,000 volunteer hours.
• Launched a new wellness platform, Thriveful, offering programs and resources for employee well-being.
• Achieved an 88% response rate and an overall engagement score of 89% in the 2022 employee pulse survey.
• 40% of new hires in the past year are persons of color, and 58% are female.

Governance Achievements

• Established an ESG working group in 2021.
• Conducted a materiality assessment in 2022 to evaluate ESG topics.
• Implemented a new cloud-based solution for contracting suppliers in August 2022.

Climate Goals & Targets

Environmental Challenges

• Relatively low environmental footprint needs more rigorous consideration as the company grows.
• Challenges in clinical trial diversity due to the nature of rare diseases.

Mitigation Strategies

• Encouraging hybrid work to reduce commute needs.
• More critically examining recruitment approaches and barriers to access in clinical trials.

Supply Chain Management

Responsible Procurement

• Risk-based approach to monitor and audit direct suppliers.

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: SASB

Awards & Recognition

• Science’s No. 1 Top Employer (2021, 2022)
• Great Place to Work in the U.S. (2021, 2022)
• Deloitte Technology Fast 500 company (2022)
• Healthier Somerset’s Gold Healthy Workplace Recognition Award (2023)

Environmental Metrics

ESG Focus Areas

• Access to Medicine
• Business Ethics
• Clinical Trial Safety
• Human Capital Development
• Product Social Responsibility
• Product & Service Safety
• Board Composition & Leadership
• Board Oversight of ESG
• Climate Change & Greenhouse Gas (GHG) Emissions
• Data Privacy & Cybersecurity
• Diversity, Equity & Inclusion
• Employee Engagement & Satisfaction
• Energy Management & Usage
• Environmental Management & Policy
• Ethical Marketing
• Supply Chain Management
• Waste Management
• Whistleblower Program

Environmental Achievements

• Completed first GHG inventory for 2023
• Cambridge, UK site procured carbon offsets for 100% of site-level GHG emissions
• Recycled 46.5 tons of waste at US headquarters and 35.6 tons at primary R&D site
• Recycled 2,320 lbs and repurposed 900 lbs of electronic waste

Social Achievements

• Launched three new ERGs (Black employees, LGBTQIA+ community, intergenerational employees) in 2023 and one in 2024 (OASIS)
• 91% employee engagement score in 2023 pulse survey
• Expanded US benefits to include wellbeing expense reimbursement, family planning support, mental health support, etc.
• Second annual Global Day of Good with over 700 employees participating and over 3,000 volunteer hours
• Supported various community organizations including Starlight Children's Foundation, Students 2 Science, Visions and Pathways, and Ronald McDonald House Charities - Japan

Governance Achievements

• Refreshed Board-approved Code of Business Conduct and Ethics in 2023
• Updated Conflicts of Interest Policy in 2023
• Hired Chief Compliance Officer in 2023
• Held Third Annual Compliance & Ethics Week in 2023
• Introduced a new whistleblower hotline managed by a third-party global compliance specialist in 2023

Climate Goals & Targets

Environmental Challenges

• Managing environmental impact of operations and resource use
• Ensuring diversity and inclusion across the workforce and clinical trials
• Maintaining high standards of ethical conduct and compliance
• Safeguarding sensitive information and protecting against cybersecurity risks

Mitigation Strategies

• Implementing sustainable solutions to mitigate environmental impact
• Establishing a Clinical Trial Diversity Task Force and partnering with vendors specializing in patient education and outreach
• Implementing a robust Global Healthcare Compliance Program with regular training and reporting mechanisms
• Strengthening cybersecurity efforts through preventative measures, continuous monitoring, and employee training

Supply Chain Management

Supplier Audits: Regular audits performed to verify compliance with regulatory standards and Insmed’s internal requirements

Responsible Procurement

• Risk-based supplier quality program
• Cloud-based supplier onboarding module to capture ESG-related information

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: SASB

Certifications: WELL Health-Safety rating

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Potential future product packaging designed to minimize environmental impact

Awards & Recognition

• Premier ERG Award from Healthier Somerset
• Visions and Pathways Corporate Honoree Recipient at its 2023 Annual Spark Gala