Atara Biotherapeutics, Inc.
Climate Impact & Sustainability Data (2023)
Reporting Period: 2023
Environmental Metrics
Social Achievements
- Implemented workforce reductions of approximately 20% in August 2022, 30% in November 2023, and 25% in January 2024 to reduce expenses and prioritize key programs.
Climate Goals & Targets
Environmental Challenges
- Substantial losses since inception and anticipation of continued losses.
- Limited commercialization revenues.
- Need for substantial additional financing.
- Potential delisting from Nasdaq.
- Uncertainties related to the Fujifilm Transaction.
- Early stage of development for most product candidates.
- Impact of health epidemics and pandemics (COVID-19).
- Dependence on regulatory approval.
- Heightened regulatory scrutiny for novel therapies.
- Small market opportunities for some product candidates.
- Potential loss of orphan drug exclusivity.
- Manufacturing risks and dependence on third parties.
- Intellectual property protection uncertainties.
- Competition in the biotechnology and pharmaceutical industries.
- Challenges in managing growth and operations.
- Stock price volatility.
- Significant stockholder ownership.
- Increased costs as a public company.
- Potential for employee misconduct.
- Product liability risks.
- Compliance with environmental, health, and safety laws.
- Compliance with privacy, data protection, and data security laws.
Mitigation Strategies
- Workforce reductions to reduce expenses.
- Plans to secure additional capital through various means.
- Transition of tab-cel manufacturing to Pierre Fabre.
- Implementation of safety protocols and procedures to support onsite workforce.
- Ongoing discussions with FDA regarding BLA submission for tab-cel.
- Development of scalable manufacturing technology.
- Negotiations with CRL for a new commercial drug product supply agreement.
- Efforts to protect intellectual property rights.
- Strategic alliances and partnerships.
- Improved managerial, operational, financial, and other procedures and processes.
- Product liability insurance coverage.
- Contracting with third parties for waste disposal.
- Implementation of robust privacy, data protection, and data security measures.