Climate Change Data

Environmental Metrics

ESG Focus Areas

• Patient well-being
• Employee well-being
• Community engagement
• Environmental sustainability
• Ethical business practices

Environmental Achievements

• Achieved energy use intensity below the average pharmaceutical facility (1.26 megawatt hour / square meters in 2017 compared to industry average of 3.81)
• Achieved LEED and ISO14001 certification of select facilities
• Replaced existing lighting with high-efficiency LED lighting, resulting in an annual savings of 107 megawatt hours

Social Achievements

• Awarded more than $2 million in educational grants to help medical professionals and others learn about mental health conditions and substance use disorders
• Awarded $1 million in ALKERMES INSPIRATION GRANTS® to support innovative community programs
• Alkermes Copayment Assistance Program and the Alkermes Patient Assistance Program helped more than 19,600 patients gain access to medication in 2017
• Recognized as a great place to work in various rankings

Governance Achievements

• Comprehensive compliance program dedicated to upholding legal, regulatory and ethical standards
• No significant adverse regulatory findings identified
• Implementation of CaRE® (Collaborative and Risk-focused Engagement) program to improve workplace safety

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Program to ensure strategic supply chain partners meet expected EHSS standards

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: Null

Certifications: LEED, ISO14001

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• National Irish Safety Organization awards (7 years)

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Combined energy use per employee decreased 13% in 2018 compared to 2017 and 37% compared to 2015.
• Water use decreased 17% in 2018 compared to 2017.
• Scope 1 greenhouse emissions decreased 8.7% in 2018 compared to 2017.

Social Achievements

• Median compensation for males and females was substantially equal across metrics of base salary, total cash compensation, and total compensation including equity (as of August 2019).
• Percentage of female employees in leadership positions (Senior Director level and above) rose from 30% to 34% from 2017 to August 2019.
• More than 18,500 patients participated in the Co-Pay Savings Program in 2018.
• Awarded more than $1.4 million in grants and charitable donations in 2018.

Governance Achievements

• Maintained an exemplary compliance record with all regulatory inspections completed successfully.
• Established a program for patients to receive access to investigational treatments outside of clinical trials.
• Implemented a robust, enterprise-wide EHSS Risk Management System (RMS).

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• EHSS risk considerations are embedded into our due diligence assessments, on-boarding procedures, technology transfers, and routine business reviews.

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: Global Reporting Initiative (GRI), United Nations Sustainable Development Goals

Certifications: ISO 14001:2015, ISO 45001:2018, ISO/IEC27001:2013

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• Not disclosed

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Combined energy use per employee decreased 13% in 2018 compared to 2017 and 37% compared to 2015.
• Scope 1 greenhouse emissions decreased 8.7% in 2018 compared to 2017.
• Water use decreased 17% in 2018 compared to 2017.

Social Achievements

• Increased percentage of female employees in leadership positions from 30% to 34% from 2017 to August 2019.
• More than 18,500 patients participated in the Co-Pay Savings Program in 2018.
• Awarded more than $1.4 million in grants and charitable donations in 2018.

Governance Achievements

• Maintained an exemplary compliance record with all regulatory inspections.
• Established a robust enterprise-wide EHSS Risk Management System (RMS).

Climate Goals & Targets

Environmental Challenges

• Not disclosed

Mitigation Strategies

• Not disclosed

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement

• Pharmaceutical Supply Chain Initiative’s ‘Pharmaceutical Industry Principles for Responsible Supply Chain Management’

Climate-Related Risks & Opportunities

Physical Risks

• Not disclosed

Transition Risks

• Not disclosed

Opportunities

• Not disclosed

Reporting Standards

Frameworks Used: GRI, UN Sustainable Development Goals

Certifications: ISO 14001:2015, ISO 45001:2018, ISO/IEC 27001:2013

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

• Not disclosed

Not disclosed

Sustainable Products & Innovation

• Not disclosed

Awards & Recognition

• Not disclosed

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Combined energy use per employee decreased 7% in 2019 compared to 2018 and 42% compared to 2015.
• Water use decreased 6% in 2019 compared to 2018, and 32% compared to 2015.
• Combined greenhouse emissions (CO2e) per employee decreased nearly 4% in 2019 compared to 2018, and 39% compared to 2015.
• Increased recycling opportunities resulting in an increase of nearly 13 metric tons of recyclable material compared to 2018 in Wilmington facility.
• Reduction in municipal water usage in Athlone facility by more than 96%.

Social Achievements

• 2019 voluntary attrition rate of 11% was below the industry benchmark of 13%.
• Established a cross-functional Diversity, Inclusion & Belonging Steering Committee.
• Created three employee resource groups: Pride@Work, Mosaic, and a women’s network.
• Percentage of female employees on the executive management team grew from 14% to 24% from 2017 to 2019.
• Conducted approximately 500 training sessions across the Company’s locations.
• More than 20,000 patients participated in the Co-Pay Savings Program.
• Awarded approximately $1.4 million in grants and charitable donations in 2019.

Governance Achievements

• Expanded shareholder engagement activities, reaching out to shareholders who collectively held more than 75% of our shares and conducting meetings with shareholders who collectively held more than 60% of our shares.
• Strengthened business, corporate governance practices and executive compensation programs.
• Appointed two new independent directors in 2019.

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic impacting patient access to medicines and employee well-being.

Mitigation Strategies

• Implemented a comprehensive crisis response strategy, including work-from-home policies, restricted travel, and enhanced safety protocols.
• Expanded injection site network to include additional pharmacies and clinics.
• Launched the Alkermes COVID-19 Relief Fund to provide grants to nonprofit organizations.

Supply Chain Management

Responsible Procurement

• Pharmaceutical Supply Chain Initiative’s ‘Pharmaceutical Industry Principles for Responsible Supply Chain Management’

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: SASB

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Energy usage per floor area in 2020 was 24% lower than the 2015 baseline.
• CO2e per floor area for combined Scope 1 and 2 GHG emissions in 2020 was 29% lower than the 2015 baseline.
• 100% of electricity used in Athlone, Ireland site was from certified renewable sources.
• 56% of total waste generated in 2020 was recycled and 21% was processed in waste-to-energy facilities.
• 95% of total hazardous waste generated in 2020 was recycled or processed in waste-to-energy facilities; no hazardous waste was sent to landfill.

Social Achievements

• Launched three employee resource groups to support inclusiveness.
• Held company-wide discussions on racism and unconscious bias.
• Enhanced diversity education offerings for employees.
• Integrated diversity into hiring and workforce development initiatives.
• Evaluated clinical trial practices to enhance patient diversity.
• 2020 voluntary attrition rate of 9.6% was below the industry benchmark of 10.5%.

Governance Achievements

• Continued membership in Business in the Community Ireland (BITCI) and working towards the “Business Working Responsibly Mark”.
• Implemented a comprehensive compliance program.
• Established a Code of Business Conduct and Ethics.
• Maintained robust policies and procedures to promote safe and sustainable research, development, manufacture and commercialization of products.

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic impacted business practices, including lower in-person attendance and changes to business travel.
• Increased activity at facilities related to COVID-19 protective measures and opening of a new facility caused overall energy usage to increase compared to 2019.

Mitigation Strategies

• Implemented work from home policies, restricted access to facilities, and transitioned field-based personnel to virtual engagements.
• Adapted workplaces, acquired protective equipment, and implemented new protocols and screening tools.
• Established a Return to the Workplace Planning Team.
• Implemented energy efficiency initiatives across facilities.

Supply Chain Management

Supplier Audits: On-site audits or tabletop reviews of all external CMOs involved in manufacturing or packaging of proprietary Alkermes medicines.

Responsible Procurement

• Vendor management and governance processes integrated with EHSS risk management procedures and formal RMS framework.
• EHSS considerations and metrics monitored and discussed in business review meetings with external operations partners.
• EHSS-related provisions incorporated into service-level agreements.

Climate-Related Risks & Opportunities

Awards & Recognition

• KeepWell Mark™
• Fitwel®
• STARR of Excellence 2020 Sponsor of the Year

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Energy usage per floor area in 2021 was 21% lower than the 2015 baseline.
• CO2e per floor area for combined Scope 1 & 2 GHG emissions in 2021 was 28% lower than the 2015 baseline.
• 100% of electricity used in Athlone, Ireland site was from certified renewable sources.
• Water use per floor space decreased by 10% in 2021 compared to 2020 and was 54% lower than the 2015 baseline.
• 63% of total waste generated in 2021 was recycled and 16% was processed in waste-to-energy facilities.
• 96% of total hazardous waste generated in 2021 was either recycled or processed in waste-to-energy facilities.

Social Achievements

• Launched two new ERGs in 2021: Limitless and Operation Salute.
• 2021 voluntary attrition rate of 12.6% was below the industry benchmark of 14.4%.
• Significant progress in gender diversity in leadership positions.
• Awarded approximately $1.6 million in research grants and charitable donations in 2021.
• More than 20,000 patients participated in Co-Pay Savings Programs in 2021.

Governance Achievements

• Athlone, Ireland facility certified to the Business Working Responsibly Mark.
• Board declassification approved and underway.
• Robust compliance program in place, including a Code of Conduct and Whistleblower Policy.
• All FDA inspections in the past 5 years classified as “No Action Indicated”.

Climate Goals & Targets

Environmental Challenges

• COVID-19 pandemic impacted operations and business practices.
• Increased absolute energy usage in 2021 due to operational growth.

Mitigation Strategies

• Comprehensive employee engagement strategy implemented to maintain business continuity and employee safety.
• Phased return to workplace plan implemented.
• Ongoing energy efficiency initiatives across facilities.

Supply Chain Management

Supplier Audits: On-site audits or tabletop reviews of all external CMOs

Responsible Procurement

• Pharmaceutical Supply Chain Initiative’s ‘Pharmaceutical Industry Principles for Responsible Supply Chain Management’

Climate-Related Risks & Opportunities

Reporting Standards

Frameworks Used: ISO 26000

Certifications: KeepWell Mark™ (Ireland sites), Business Working Responsibly Mark (Athlone site)

Awards & Recognition

• KeepWell Mark™
• Ireland’s Leading in Wellbeing Top 100 Companies 2021
• Best in Class Nutrition award

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Lost workday case rate in 2022 was 0.1, compared to the industry benchmark of 0.7.
• Recordable incident rate in 2022 was 0.4, compared to the industry benchmark of 1.5.
• Water use per floor space (cubic meters per m2) was 47% lower than our 2015 baseline measurement year.
• 90% of total waste generated in 2022 was recycled, representing a significant increase from 63% recycled in 2021.
• 97% of total hazardous waste generated in 2022 was either recycled or processed in waste-to-energy facilities.
• Energy usage per floor area (kWhr/m2) in 2022 was 17% lower than our 2015 baseline measurement year.
• CO2e per floor area (m2) for combined Scope 1 and 2 GHG emissions in 2022 was 27% lower than our 2015 baseline year.
• 100% of electricity used in our Dublin offices and our Athlone R&D and manufacturing site was from certified renewable sources.

Social Achievements

• 2022 voluntary attrition rate of 9.5% was below the industry benchmark of 12.6%.
• Hosted nearly 20 DIB-related education, awareness and training programs with total aggregate attendance of approximately 2,800 employees.
• Implemented an annual performance goal focused on DIB for all senior leaders.
• Awarded the Bell Seal at the Platinum Level from Mental Health America.

Governance Achievements

• Established an Executive ESG Committee to oversee ESG strategy, risks and opportunities.
• All FDA inspections of Alkermes sites in the past 5 years have been classified as “No Action Indicated”.

Climate Goals & Targets

Environmental Challenges

• Overall absolute source water usage at our facilities increased 15% in 2022 compared to 2021, primarily due to groundwater well repair work at our Athlone facility.
• Overall energy use increased sequentially by 4% in 2022, and in turn our combined Scope 1 & 2 GHG emissions (absolute) increased by 2%.

Mitigation Strategies

• The majority of the water used in repair work was recovered and recycled.
• Increases in energy use and GHG emissions were partially mitigated by continued assessment and implementation of opportunities to improve energy use and reduce GHG emissions at our facilities, including the use of 100% renewable electricity at Dublin offices and Athlone facility and installation of a dedicated chilled water unit at Athlone facility.

Supply Chain Management

Responsible Procurement

• Supplier diversity program; engagement with certifying authorities and NGOs; EcoVadis assessment of suppliers.

Climate-Related Risks & Opportunities

Awards & Recognition

• 2022 Platinum Bell Seal for Workplace Mental Health
• 2022 Healthiest Employers® of Ohio
• 2022 Best Place for Working Parents® in Massachusetts
• Business Working Responsibly Mark
• KeepWell Mark™

Environmental Metrics

ESG Focus Areas

• Environment
• Social
• Governance

Environmental Achievements

• Energy usage per floor area (kWhr/m2) in 2023 was 16% lower than our 2015 initial baseline measurement year and generally consistent with 2022 usage.
• CO2 per floor area (m2) for combined Scope 1 and Scope 2 GHG emissions in 2023 was 29% lower than our 2015 initial baseline year and 2% lower compared to 2022.
• 100% of electricity used in our Athlone facility was from certified renewable sources, which helped to offset our Scope 2 GHG emissions.
• In October 2023, our Ohio facility entered into an agreement to procure 30% of electricity from renewable sources going forward.
• Water use per floor space (cubic meters per m2) was 53% lower than our 2015 initial baseline measurement year and 12% lower compared to 2022.
• 82% of total waste generated in 2023 was recycled, and 12% was processed in waste-to-energy facilities.
• 97% of total hazardous waste generated in 2023 was either recycled or processed in waste-to-energy facilities.

Social Achievements

• Introduced a new four-week, fully paid caregiver leave benefit for U.S. employees.
• Expanded paid parental leave for U.S. employees.
• Supplemented on-site physical wellness activities with holistic virtual health coaching.
• Provided more than 130 unique opportunities for professional training and development.
• Hosted nearly 20 events focused on diversity, inclusion and belonging across our sites.
• 2023 voluntary attrition rate of 9.5% was below the industry benchmark of 11.4%.

Governance Achievements

• Declassified Board, with each director up for re-election annually.
• 45% of the Board is diverse in terms of gender or race/ethnicity.
• Maintained an annual performance goal focused on DIB for all senior leaders (VP level and above).

Climate Goals & Targets

Environmental Challenges

• Minimizing environmental impacts of operations.
• Maintaining a diverse and inclusive workplace.

Mitigation Strategies

• Implemented enterprise-wide EHSS initiatives and management strategies.
• Developed and implemented a Diversity, Inclusion and Belonging (DIB) strategy.
• Engaged with EcoVadis to evaluate suppliers on ESG metrics.

Supply Chain Management

Supplier Audits: More than 100 suppliers evaluated through EcoVadis.

Responsible Procurement

• ESG considerations embedded in procurement and supply chain vendor management processes.
• Pharmaceutical Supply Chain Initiative’s ‘Pharmaceutical Industry Principles for Responsible Supply Chain Management’ used for vendor assessment.

Climate-Related Risks & Opportunities

Awards & Recognition

• Bell Seal for Workplace Mental Health (Platinum Level)
• Healthiest Employers® of Ohio
• Best Place for Working Parents® in Massachusetts
• WorkWell Award® from Worksite Wellness Council of Massachusetts
• Health & Safety Excellence Award in Ireland
• Business Working Responsibly Mark (based on ISO26000)
• Award for Safety in Maintenance and Asset Management from the Engineers Ireland Maintenance, Energy and Environmental Technology Association (MEETA)