Climate Change Data

Cizzle Biotechnology Holdings PLC

Climate Impact & Sustainability Data (2023)

Reporting Period: 2023

Environmental Metrics

Total Carbon Emissions:Not disclosed
Scope 1 Emissions:Not disclosed
Scope 2 Emissions:Not disclosed
Scope 3 Emissions:Not disclosed
Renewable Energy Share:Not disclosed
Total Energy Consumption:Less than 40,000 kWh/year
Water Consumption:Not disclosed
Waste Generated:Not disclosed
Carbon Intensity:Not disclosed

ESG Focus Areas

  • Environmental
  • Social
  • Governance

Environmental Achievements

  • Adopted a rigorous recycling regime for polypropylene and polystyrene items used in mammalian cell culture at the University of York.

Social Achievements

  • Not disclosed

Governance Achievements

  • Adopted the Quoted Companies Alliance’s Corporate Governance Code.

Climate Goals & Targets

Long-term Goals:
  • Not disclosed
Medium-term Goals:
  • Achieve UKCA, CE marking, and/or FDA 510(k) clearance for the CIZ1B test.
  • Expand into global markets (USA, Canada, China).
Short-term Goals:
  • Complete the first commercial test to detect CIZ1B.
  • Further protect the Group’s Intellectual Property (IP).

Environmental Challenges

  • Pre-revenue business with operating losses and reliance on CIZ1B biomarker success.
  • Regulatory hurdles (UKCA, CE Marking, FDA 510(k) clearance, LDT accreditation) for product launch.
  • Competition from other cancer detection tests.
  • Attracting and retaining key management and employees.
  • Complex and bespoke reagents and components for the test.
  • Protection of intellectual property rights.
  • Lack of manufacturing process (outsourcing required).
  • Future funding requirements.
  • Meeting project milestones for commercialization.
  • Economic uncertainty and potential cost pressures.
Mitigation Strategies
  • Secured funding through share issues and a Memorandum of Understanding (MoU) with Cizzle Bio Inc for North American licensing.
  • Intends to pursue regulatory clearance via retrospective testing data, with a prospective study as a backup.
  • Closely monitoring regulatory changes and working with MHRA.
  • Providing incentives to retain key employees.
  • Regular appraisal of project milestones and various strategies.
  • Regular monitoring of third-party patents/IPR with patent advisors.
  • Outsourcing manufacturing to a specialized partner.
  • Developing multiple funding scenarios.
  • Continual review of project milestones at monthly operational and board meetings.
  • Negotiating fixed-price contracts with professional advisors.

Supply Chain Management

Supplier Audits: Not disclosed

Responsible Procurement
  • Not disclosed

Climate-Related Risks & Opportunities

Physical Risks
  • Not disclosed
Transition Risks
  • Not disclosed
Opportunities
  • Not disclosed

Reporting Standards

Frameworks Used: TCFD

Certifications: Null

Third-party Assurance: Not disclosed

UN Sustainable Development Goals

  • Not disclosed

Not disclosed

Sustainable Products & Innovation

  • Not disclosed

Awards & Recognition

  • Not disclosed