Climate Change Data

Environmental Metrics

ESG Focus Areas

• Innovation and Drug Discovery
• Patient Advocacy and Engagement
• Workplace Culture
• Diversity, Equity and Inclusion
• Environmental Sustainability
• Governance and Integrity

Environmental Achievements

• Achieved 51% renewable energy use in 2023 with 17% of electricity from renewable sources generated onsite.
• 24% reduction in water use since 2021 (12.85 million gallons in 2023)
• New condensate water collection system for reuse in cooling tower at Carlsbad headquarters.
• New state-of-the-art research and development facility under construction, aiming for LEED Gold certification.

Social Achievements

• Launched Ionis VisION Awards, recognizing six outstanding employees.
• Launched new corporate DEI site and dashboard.
• Expanded employee resource groups to nine.
• 1,400+ hours of employee volunteering.
• 73% employee engagement in 2023 survey.
• Voluntary turnover rate of 5.2% (well below industry average).

Governance Achievements

• Conducted first CR materiality assessment.
• Expanded Corporate Responsibility Steering Committee.
• Over 95% of employees completed Code of Ethics and Business Conduct training.
• Hired a Data Privacy Officer and appointed a Chief Information Security and Compliance Officer.

Climate Goals & Targets

Environmental Challenges

• Increased Scope 1 and 2 GHG emissions by 18% since 2021 (despite emissions intensity per employee decreasing by 15%).
• Potential climate change-related risks including extreme weather events and regulatory changes.

Mitigation Strategies

• Investing in technology and infrastructure to reduce electricity use (solar energy systems, energy efficiency programs).
• Incorporating energy-efficient design into new facilities.
• Developing action plans to address material risks and opportunities identified in the CR materiality assessment.
• Scenario analysis planned for 2025 to evaluate impact of climate-related risks and opportunities.

Supply Chain Management

Climate-Related Risks & Opportunities

Physical Risks

• Extreme weather events
• Natural disasters

Transition Risks

• Regulatory changes
• Potential carbon tax or regulatory incentives

Reporting Standards

Frameworks Used: SASB, TCFD

Certifications: AAALAC

Awards & Recognition

• 2023 Rainwater Prize
• 2023 Drs. Ayeez and Shelena Lalji and Family ALS Endowed Award